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Liposomal FISETIN

A Clinically Proven Senolytic Compound

Made With A Pharmaceutical-Grade Liposomal Encapsulation Technology For Maximum Absorption & Effectiveness

  • Protects Against Cellular Damage
  • Helps Reduce Harmful Inflammation
  • Enhances Cognitive Functions
  • Improves Health & Extends Lifespan
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Fisetin: The World’s
Most Powerful Senolytic

Findings: Of the 10 flavonoids tested, fisetin was the most potent senolytic.”

– EBioMedicine

In 2018, a study was published by EBioMedicine titled: “Fisetin is a senotherapeutic that extends health and lifespan”.

Fisetin, as you may know, is a flavonoid found in various fruits and vegetables. But perhaps the most intriguing fact is that this plant compound has a special “superpower” for eliminating “zombie” cells, also known as senescent cells.

These unwanted “guests” – lurking inside the body – are called “zombie” cells because they are damaged and dysfunctional, but refuse to die. And over time, as we get older, these cells accumulate. This is bad news, because according to recent research this accumulation triggers a myriad of health problems, while also accelerating the aging process.

But the exciting news is the latest research and clinical studies are reporting amazing results by supplementing with Fisetin for the elimination of “zombie” cells, while improving health and extending lifespan.

Clinically Recommended &
Safe Dosage

Importantly, no adverse effects of fisetin have been reported, even when given at high doses.Thus, our results suggest that supplementation with this safe, natural product could improve healthy aging, even in elderly individuals. ”

– EBioMedicine

Studies on fisetin have been performed with as little as 20 mg all the way up to 1,500 mg or more. And the research shows fisetin is well tolerated with daily supplementation. However, with fisetin, a little goes a long way. And preliminary research is showing how smaller doses could be more beneficial than larger doses. That’s why our formula is made with a clinically studied dose of 150 mg of fisetin. In fact, one of the most compelling animal studies was on young mice given fisetin which resulted in a reduction in senescent cells in white adipose tissue, in just 5 days. And with GenuinePurity™ Liposomal Fisetin you’re getting an ultra-pure 150 mg dose every time. Safe. Proven. Effective.

Optimized For Maximum Effectiveness With Liposomal Encapsulation Technology

Our state-of-the-art formula is made with a liposomal encapsulation technology that helps increase the effectiveness of fisetin in three distinct ways:


Forms a safeguarding “shield,” protecting the fisetin from stomach acids and preserving the integrity


Amplifies solubility, simplifying the absorption process for the fisetin to enter your bloodstream effortlessly


Elevates cellular uptake by facilitating liposomal fusion with cell membranes, ensuring the fisetin is delivered directly to
your cells

Certified Authentic Fisetin

Now that the compelling research about this powerful senolytic compound is becoming more mainstream, it seems like fisetin products are popping up every day. Unfortunately, many of these products are made by fly-by-night companies that are selling fake fisetin. Here today. Gone tomorrow. No quality check. And certainly no refund policy.

That’s why GenuinePurity™ is proud to present our Certificate of Analysis with every formula, including Liposomal Fisetin. This way you know you’re getting the “real deal” and not getting ripped off. Just click the image to confirm the authenticity of our formula for yourself.

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A Potent Antioxidant for Protecting Against
Oxidative Stress & Cellular Damage

[Fisetin] acts as an antioxidant … maintains mitochondrial function in the presence of oxidative stress…”

– Antioxidant & Redox Signaling

Fisetin is a flavonoid that exhibits potent antioxidant properties and protects the cells against oxidative stress”

– Frontiers

Antioxidant Properties

Fisetin is known to possess antioxidant properties, meaning it can neutralize reactive oxygen species (ROS) and free radicals in the body. Oxidative stress, caused by an imbalance between the production of these harmful molecules and the body’s ability to detoxify them, can contribute to cellular damage. Fisetin’s antioxidant activity helps counteract oxidative stress.

Activation of Cellular Defense Mechanisms

Fisetin may activate various cellular defense mechanisms, including the expression of antioxidant enzymes. By enhancing the activity of these enzymes, fisetin may contribute to the body’s ability to cope with oxidative stress and maintain cellular health.

Mitochondrial Protection

Mitochondria are the energy-producing organelles in cells, and they are vulnerable to oxidative damage. Fisetin has been suggested to protect mitochondria from oxidative stress, helping to maintain their function and integrity.

Helps Reduce
Harmful Inflammation

Recent clinical trials have reported that fisetin (100 mg) supplements taken for seven consecutive weeks significantly reduced inflammation markers”

– International Journal of Molecular Sciences

[Fisetin] inhibits the production of pro-inflammatory cytokines and enzymes, which can help to reduce inflammation in the body”

– ScienceDirect

Inhibition of Inflammatory Mediators

Fisetin has been shown to inhibit the production and activity of various pro-inflammatory molecules, such as cytokines and chemokines. These molecules play key roles in the inflammatory response. By reducing their expression and function, fisetin may help dampen the overall inflammatory process.

Modulation of Inflammatory Pathways

Fisetin may interfere with specific signaling pathways involved in inflammation. For example, it has been found to inhibit the activation of nuclear factor-kappa B (NF-κB), a transcription factor that plays a central role in regulating inflammatory responses. By modulating these pathways, fisetin may help regulate the inflammatory cascade.

Inhibition of Inflammatory Enzymes

Fisetin has been reported to inhibit the activity of certain enzymes, such as cyclooxygenase-2 (COX-2) and lipoxygenase, which are involved in the synthesis of pro-inflammatory molecules called prostaglandins and leukotrienes. Inhibiting these enzymes can help modulate the inflammatory response.

Enhances Metabolic Health

Fisetin … possesses potential neuroprotective effects. Fisetin also enhances learning and memory, decreases neuronal cell death, and suppresses oxidative stress.”

– Current Topics in Medicinal Chemistry

Fisetin is effective at preventing loss of cognitive function and maintaining brain health in multiple, distinct models of dementia.”

– Brain Plasticity

Neurotrophic Effects

Fisetin has been suggested to promote the production of brain-derived neurotrophic factor (BDNF). BDNF is a protein that supports the growth, survival, and differentiation of neurons. Higher levels of BDNF are generally associated with better cognitive function and neuroplasticity.

Anti-Amyloid Properties

Fisetin has shown potential in inhibiting the aggregation of beta-amyloid peptides. Beta-amyloid accumulation is a hallmark of neurological problems, and substances that can interfere with this process may have neuroprotective effects.

Modulation of Signaling Pathways

Fisetin may influence various cellular signaling pathways associated with synaptic plasticity, neuronal survival, and cognitive function. For example, it has been reported to modulate the mTOR pathway, which plays a role in cellular processes related to neuroprotection and cognition.

Improves Cardiovascular Function

…Fisetin treatment improved cardiac function…”

– International Heart Journal

Additionally, fisetin attenuated LPS-induced mortality and abnormalities in zebrafish larvae and normalized the heart rate.”

– Scientific Reports

Improvement in Lipid Profile

Fisetin has been studied for its potential to influence lipid metabolism. Some research suggests that fisetin may help improve lipid profiles by reducing levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides, while increasing high-density lipoprotein cholesterol (HDL-C). Maintaining a favorable lipid profile is crucial for cardiovascular health.


Fisetin has been reported to have vasodilatory effects, meaning it may help relax blood vessels, improve blood flow, and reduce blood pressure. Vasodilation can contribute to better cardiovascular function and reduced strain on the heart.

Antiplatelet Activity

Fisetin has been investigated for its potential antiplatelet effects, meaning it may interfere with the aggregation of blood platelets. Excessive platelet aggregation can contribute to the formation of blood clots, which is a risk factor for unwanted cardiovascular events.

Improves Health
& Extends Lifespan

Fisetin is a senotherapeutic that extends health and lifespan”

– Mayo Clinic

Fisetin… has been found to have a significant positive effect on the health and longevity of older mice.”

– Plant Foods for Human Nutrition

Senolytic Activity

Fisetin has been identified as a senolytic compound, meaning it has the potential to selectively eliminate senescent cells. Senescent cells are aged cells that have stopped dividing but remain metabolically active and can contribute to tissue dysfunction and inflammation. By targeting and removing these cells, fisetin may contribute to improved overall health and potentially extend lifespan.

Enhancement of Cellular Health

Fisetin has been studied for its ability to support mitochondrial function and cellular health. Mitochondrial dysfunction is linked to aging, and fisetin’s potential to promote mitochondrial health may contribute to longevity.

DNA Repair

Oxidative stress can lead to damage in cellular DNA. Fisetin has been investigated for its potential to support DNA repair mechanisms, which is crucial for maintaining genomic stability and preventing the accumulation of mutations that can contribute to various health issues.

Understanding the Senolytic Role of Fisetin

Fisetin reduced senescence in a subset of cells in murine and human adipose tissue”

– MDPI – Antioxidants

Senescent cells, also known as “zombie” cells” – are damaged cells in the body that accumulate with age. These cells are known to alter gene expression, cause DNA damage and contribute to the aging process.

Fisetin is known as a senolytic compound because research shows it eliminates senescent cells. In fact, fisetin is known as the most potent senolytic on the planet. And studies show that when senescent cells are “killed”, health improves and lifespan extends.

You’re Invited to
Try Our Product for 97 Days

Our promise to you is simple: If, for any reason, you are not 100% satisfied, simply return the empty containers within 97 days from the time of delivery for a full refund excluding shipping charges.

If you wish to take advantage of the price discount by ordering multiple containers, don’t worry! Any unopened containers returned along with your opened containers within the 90-day money-back guarantee period will also be eligible for a full refund less any shipping charges.

That said, we must respectfully remind you not to ship back any product after the refund period has expired. Returns must be received back at the warehouse within 97 days of delivery with no exceptions. Please note that we must limit refunds to one order per customer.

Proudly Made In The USA, In cGMP-Certified Facilities

GenuinePurity™ Fisetin is made in cGMP-certified facilities, right here in the USA, to ensure the highest quality possible. This means we follow the highest manufacturing standards so you can feel confident every time you order our formulas.

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Continental USA

Please allow us to cover the delivery costs with free shipping on all orders in the continental USA.

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Frequently Asked Questions About GenuinePurity Fisetin

Fisetin is a flavonoid found in various fruits and vegetables known for its senolytic effects. In fact, research shows fisetin is the most powerful senolytic compound in the world - shown to eliminate about 70% of senescent cells.

Zombie cells are also known as senescent cells - dysfunctionial or damaged cells that accumulate in the body contributing to a myriad of health issues, which includes accelerating the aging process.

Our single-ingredient formula contains an ultra-pure form of naturally-derived fisetin.

Each daily dose of 1 capsule contains a clinically studied dose of 150 mg of Fisetin.

Simply take 1 capsule daily, preferably with a meal.

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